November 2006
Characterization of Helicobacter pylori Lytic Transglycosylases Slt and MltD
C. Chaput, A. Labigne and I. G. Boneca
Original research paper: Journal of Bacteriology 189
doi:10.1128/JB.01270-06Cloning of a Cholesterol- -glucosyltransferase from Helicobacter pylori
A.-H. Lebrun
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M603345200Understanding the Biological Rationale for the Diversity of Cellulose-directed Carbohydrate-binding Modules in Prokaryotic Enzymes
A. W. Blake
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M605903200Cj1121c, a Novel UDP-4-keto-6-deoxy-GlcNAc C-4 Aminotransferase Essential for Protein Glycosylation and Virulence in Campylobacter jejuni
S. Vijayakumar
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M511714200The Structure of the Major Cell Wall Polysaccharide of Bacillus anthracis Is Species-specific
B. Choudhury
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M605768200The herpesvirus glycoproteins B and H{middle dot}L are sequentially recruited to the receptor-bound gD to effect membrane fusion at virus entry
T. Gianni
Original research paper: Proceedings of the National Academy of Sciences 103
doi:10.1073/pnas.0606127103The love–hate relationship between bacterial polysaccharides and the host immune system
Sarkis K. Mazmanian and Dennis L. Kasper
Original research paper: Nature Reviews Immunology 6 849-858 (2006)
doi:10.1038/nri1956Targeting of CD44 eradicates human acute myeloid leukemic stem cells
Liqing Jin et al.
Original research paper: Nature Medicine 12 1167-1174 (2006)
doi:10.1038/nm1483Identification of a novel cancer-specific immunodominant glycopeptide epitope in the MUC1 tandem repeat
M. A. Tarp et al.
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwl061Effect of membrane-bound IgG and desialysation in the interaction of monocytes with senescent erythrocytes
A. Ensinck et al.
Original research paper: Clinical and Experimental Medicine 6
doi:10.1007/s10238-006-0110-yComplement targeting of nonhuman sialic acid does not mediate cell death of human embryonic stem cells
María Jesús Martín, Alysson Muotri, Fred H. Gage and Ajit Varki
Original research paper: Nature Medicine 12 1115
doi:10.1038/nm1006-1115Complement targeting of nonhuman sialic acid does not mediate cell death of human embryonic stem cells
Chantal Cerdan et al.
Original research paper: Nature Medicine 12 1113-1114
doi:10.1038/nm1006-1113An N-Linked Glycan Modulates the Interaction between the CD1d Heavy Chain and beta2-Microglobulin
C. Paduraru et al.
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M608518200Multiple Antigenic Mimotopes of HIV Carbohydrate Antigens: Relating Structure and Antigenicity
A. D. Pashov
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M604137200Monocyte Differentiation Up-regulates the Expression of the Lysosomal Sialidase, Neu1, and Triggers Its Targeting to the Plasma Membrane via Major Histocompatibility Complex Class II-positive Compartments
F. Liang
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M605633200Galactosylation of IgG from rheumatoid arthritis (RA) patients – changes during therapy
Marta Pasek et al.
Original research paper: Glycoconjugate Journal 23
doi:10.1007/s10719-006-5409-0Molecular mechanisms of muscular dystrophies: old and new players
Kay E Davies and Kristen J Nowak
Original research paper: Nature Reviews Molecular Cell Biology 7 762-773 (2006)
doi:10.1038/nrm2024Inhibition of influenza-virus-induced cytopathy by sialylglycoconjugates
T Terabayashi et al.
Original research paper: Carbohydrate Research 341
doi:10.1016/j.carres.2006.06.017Advanced glycation end product (AGE) receptor 1 suppresses cell oxidant stress and activation signaling via EGF receptor
W. Cai
Original research paper: Proceedings of the National Academy of Sciences 103
doi:10.1073/pnas.0600362103Structure and function relations with a T-cell-activating polysaccharide antigen using circular dichroism
L. S.C. Kreisman, J. H. Friedman, A. Neaga and B. A. Cobb
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwl056Monitoring of heparin and its low-molecular-weight analogs by silicon field effect
N. M. Milovic
Original research paper: Proceedings of the National Academy of Sciences 103
doi:10.1073/pnas.0604471103Sweetening up yeast glycoprotein synthesis
Allison Doerr
Original research paper: Nature Methods 3 874
doi:10.1038/nmeth1106-874bUsing substrate engineering to harness enzymatic promiscuity and expand biological catalysis
Luke L Lairson, Andrew G Watts, Warren W Wakarchuk and Stephen G Withers
Original research paper: Nature Chemical Biology 2 724-728 (2006)
doi:10.1038/nchembio828N-Glycan structures and N-glycosylation sites of mouse soluble intercellular adhesion molecule-1 revealed by MALDI-TOF and FTICR mass spectrometry
V. I. Otto
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl032Synthesis of new analogues of salacinol containing a pendant hydroxymethyl group as potential glycosidase inhibitors
R Nasi and B Pinto
Original research paper: Carbohydrate Research 341
doi:10.1016/j.carres.2006.06.022A facile synthesis of 1,6-dideoxynojirimycin from l-sorbose
J An, X Meng, Y Yao and Z Li
Original research paper: Carbohydrate Research 341
doi:10.1016/j.carres.2006.06.002A Novel -Helix in the First Fibronectin Type III Repeat of the Neural Cell Adhesion Molecule Is Critical for N-Glycan Polysialylation
S. S. Mendiratta et al.
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M608073200Spacer-separated sialyl LewisX cyclopeptide conjugates as potential E-selectin ligands
H Herzner and H Kunz
Original research paper: Carbohydrate Research
doi:10.1016/j.carres.2006.09.012Human complement factor I glycosylation: Structural and functional characterisation of the N-linked oligosaccharides
S Tsiftsoglou et al.
Original research paper: Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics 1764
doi:10.1016/j.bbapap.2006.09.007Why does avian influenza A virus hemagglutinin bind to avian receptor stronger than to human receptor? Ab initio fragment molecular orbital studies
T Sawada et al.
Original research paper: Biochemical and Biophysical Research Communications 351
doi:10.1016/j.bbrc.2006.09.165Identification of the Sialic Acid Structures Recognized by Minute Virus of Mice and the Role of Binding Affinity in Virulence Adaptation
H.-J. Nam
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M604421200Structure of the Epstein-Barr virus major envelope glycoprotein
Gerda Szakonyi et al.
Original research paper: Nature Structural & Molecular Biology 13 996-1001 (2006)
doi:10.1038/nsmb1161Structural insights into the Notch-modifying glycosyltransferase Fringe
Martin Jinek et al.
Original research paper: Nature Structural & Molecular Biology 13 945-946 (2006)
doi:10.1038/nsmb1144Structural elucidation of the O-antigenic polysaccharide from enterohemorrhagic (EHEC) Escherichia coli O48:H21
L Maclean, A Webb and M Perry
Original research paper: Carbohydrate Research 341
doi:10.1016/j.carres.2006.08.008Synthesis of novel σ-receptor ligands from methyl α-d-mannopyranoside
K Wiedemeyer and B Wunsch
Original research paper: Carbohydrate Research 341
doi:10.1016/j.carres.2006.06.016Physicochemical properties and antitumor activities of water-soluble native and sulfated hyperbranched mushroom polysaccharides
Y Tao, L Zhang and P Cheung
Original research paper: Carbohydrate Research 341
doi:10.1016/j.carres.2006.05.024Clearance mechanism of a mannosylated antibody-enzyme fusion protein used in experimental cancer therapy
H. Kogelberg et al.
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwl053Cyanovirin-N Inhibits Hepatitis C Virus Entry by Binding to Envelope Protein Glycans
F. Helle
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M602431200A sugar switch for anti-inflammatory antibodies
Roy Jefferis
Original research paper: Nature Biotechnology 24 1230-1231
doi:10.1038/nbt1006-1230Sulfated L-selectin ligands as a therapeutic target in chronic inflammation
K Uchimura and S Rosen
Original research paper: Trends in Immunology 27
doi:10.1016/j.it.2006.10.007Detection of oligosaccharide ligands for Hepatocyte growth factor/Scatter factor (HGF/SF), Keratinocyte growth factor (KGF/FGF-7), RANTES and Heparin cofactor II by neoglycolipid microarrays of glycosaminoglycan-derived oligosaccharide fragments
Keiko Yamaguchi, Hirotoshi Tamaki and Shigeyuki Fukui
Original research paper: Glycoconjugate Journal 23
doi:10.1007/s10719-006-7151-zN-Glycosylation of Fibroblast Growth Factor Receptor 1 Regulates Ligand and Heparan Sulfate Co-receptor Binding
L. Duchesne
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M601248200Sweet deception
Shannon Amoils
Original research paper: Nature Reviews Microbiology 4 802-803
doi:10.1038/nrmicro1545Neural Cell Adhesion Molecule-associated Polysialic Acid Inhibits NR2B-containing N-Methyl-D-aspartate Receptors and Prevents Glutamate-induced Cell Death
M. S. L. Hammond et al.
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M602568200N-Glycosylation of the beta-Propeller Domain of the Integrin 5 Subunit Is Essential for 5beta1 Heterodimerization, Expression on the Cell Surface, and Its Biological Function
T. Isaji et al.
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M607771200CKAP4/p63 Is a Receptor for the Frizzled-8 Protein-related Antiproliferative Factor from Interstitial Cystitis Patients
T. P. Conrads et al.
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M604581200Sialoadhesin deficiency ameliorates myelin degeneration and axonopathic changes in the CNS of PLP overexpressing mice
C Ip et al.
Original research paper: Neurobiology of Disease 25
doi:10.1016/j.nbd.2006.08.023A male contraceptive targeting germ cell adhesion
Dolores D Mruk, Ching-Hang Wong, Bruno Silvestrini and C Yan Cheng
Original research paper: Nature Medicine 12 1323-1328 (2006)
doi:10.1038/nm1420Down-regulation of 1,4-galactosyltransferase V is a critical part of etoposide-induced apoptotic process and could be mediated by decreasing Sp1 levels in human glioma cells
J. Jiang
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl027Oligosaccharides modulate the apoptotic activity of glycodelin
R. Jayachandran
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl024Preferential transfer of the complete glycan is determined by the oligosaccharyltransferase complex and not by the catalytic subunit
O. Castro, F. Movsichoff and A. J. Parodi
Original research paper: Proceedings of the National Academy of Sciences 103
doi:10.1073/pnas.0607086103Structural and biochemical studies of the C-terminal domain of mouse peptide-N-glycanase identify it as a mannose-binding module
X. Zhou et al.
Original research paper: Proceedings of the National Academy of Sciences 103
doi:10.1073/pnas.0602954103N-Acetylglucosaminyltransferase III Antagonizes the Effect of N-Acetylglucosaminyltransferase V on 3beta1 Integrin-mediated Cell Migration
Y. Zhao et al.
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M607274200Fucosylation of N-Glycans Regulates the Secretion of Hepatic Glycoproteins into Bile Ducts
T. Nakagawa
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M605697200UDP-Gal: GlcNAc-R β1,4-galactosyltransferase—a target enzyme for drug design. Acceptor specificity and inhibition of the enzyme
Inka Brockhausen et al.
Original research paper: Glycoconjugate Journal 23
doi:10.1007/s10719-006-7153-xComparative characterisation of recombinant invertebrate and vertebrate peptide O-Xylosyltransferases
Andrea Brunner et al.
Original research paper: Glycoconjugate Journal 23
doi:10.1007/s10719-006-7633-zCloning and biochemical characterization of the fucanase FcnA: definition of a novel glycoside hydrolase family specific for sulfated fucans
S. Colin
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl029Procyclic Trypanosoma brucei Expresses Separate Sialidase and trans-Sialidase Enzymes on Its Surface Membrane
G. N. Montagna, J. E. Donelson and A. C. C. Frasch
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M604951200Identification of Common and Unique Peptide Substrate Preferences for the UDP-GalNAc:Polypeptide -N-acetylgalactosaminyltransferases T1 and T2 Derived from Oriented Random Peptide Substrates
T. A. Gerken, J. Raman, T. A. Fritz and O. Jamison
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M605149200Substrate Specificity Analysis of Endoplasmic Reticulum Glucosidase II Using Synthetic High Mannose-type Glycans
K. Totani, Y. Ihara, I. Matsuo and Y. Ito
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M605457200Polysialic Acid Profiles of Mice Expressing Variant Allelic Combinations of the Polysialyltransferases ST8SiaII and ST8SiaIV
S. P. Galuska et al.
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M606516200The CMP-sialic Acid Transporter Is Localized in the Medial-Trans Golgi and Possesses Two Specific Endoplasmic Reticulum Export Motifs in Its Carboxyl-terminal Cytoplasmic Tail
W. Zhao, T.-L. L. Chen, B. M. Vertel and K. J. Colley
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M605564200Roles for UDP-GlcNAc 2-Epimerase/ManNAc 6-Kinase outside of Sialic Acid Biosynthesis: MODULATION OF SIALYLTRANSFERASE AND BiP EXPRESSION, GM3 AND GD3 BIOSYNTHESIS, PROLIFERATION, AND APOPTOSIS, AND ERK1/2 PHOSPHORYLATION
Z. Wang
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M604903200Exploiting the Reversibility of Natural Product Glycosyltransferase-Catalyzed Reactions
C. Zhang
Original research paper: Science 313
doi:10.1126/science.1130028Modification of p53 with O-linked N-acetylglucosamine regulates p53 activity and stability
Won Ho Yang et al.
Original research paper: Nature Cell Biology 8 1074-1083 (2006)
doi:10.1038/ncb1470Differentiation elicits negative regulation of human β-galactoside α2,6-sialyltransferase at the mRNA level in the HL-60 cell line
A Taniguchi
Original research paper: FEBS Letters 441
doi:10.1016/S0014-5793(98)01548-8Unique disialosyl gangliosides from salmon kidney: Characterization of V3αFuc, IV3βGalNAc, II3(αNeuAc)2-Gg4Cer and its analogue with 4-O-acetyl-N-acetylneuraminic acid
Yukio Niimura and Ineo Ishizuka
Original research paper: Glycoconjugate Journal 23
doi:10.1007/s10719-006-6562-1Genetic mechanisms for the synthesis of fucosyl GM1 in small cell lung cancer cell lines
N. Tokuda
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl022Serglycin Is the Major Secreted Proteoglycan in Macrophages and Has a Role in the Regulation of Macrophage Tumor Necrosis Factor- Secretion in Response to Lipopolysaccharide
L. Zernichow
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M512889200G-CSF induces E-selectin ligand expression on human myeloid cells
Nilesh M Dagia et al.
Original research paper: Nature Medicine 12 1185-1190 (2006)
doi:10.1038/nm1470Regulation of effector T cells by antigen-presenting cells via interaction of the C-type lectin MGL with CD45
Sandra J Van vliet, Sonja I Gringhuis, Teunis B H Geijtenbeek and Yvette Van kooyk
Original research paper: Nature Immunology 7 1200-1208 (2006)
doi:10.1038/ni1390Galectin-8 and galectin-9 are novel substrates for thrombin
N. Nishi
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl028Chondroitin Sulfate Perlecan Enhances Collagen Fibril Formation: IMPLICATIONS FOR PERLECAN CHONDRODYSPLASIAS
A. J. Kvist et al.
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M607892200Heparan Sulfate-related Oligosaccharides in Ternary Complex Formation with Fibroblast Growth Factors 1 and 2 and Their Receptors
N. Jastrebova
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M600806200Matrix morphogenesis in cornea is mediated by the modification of keratan sulfate by GlcNAc 6-O-sulfotransferase
Y. Hayashida
Original research paper: Proceedings of the National Academy of Sciences 103
doi:10.1073/pnas.0605441103Arraying glycomics: a novel bi-functional spacer for one-step microscale derivatization of free reducing glycans
O. Bohorov, H. Andersson-sand, J. Hoffmann and O. Blixt
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl044Lectindb: a plant lectin database
N. R. Chandra
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl012Search for glucose/galactose-binding proteins in newly discovered protein sequences using molecular modeling techniques and structural analysis
M. Patra
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl021Glycan microarray technologies: tools to survey host specificity of influenza viruses
James Stevens, Ola Blixt, James C. Paulson and Ian A. Wilson
Original research paper: Nature Reviews Microbiology 4 857-864 (2006)
doi:10.1038/nrmicro1530Mining the Molecules That Made Our Mind
E. Pennisi
Original research paper: Science 313
doi:10.1126/science.313.5795.1908Down-regulation of trypsinogen expression is associated with growth retardation in 1,6-fucosyltransferase-deficient mice: attenuation of proteinase-activated receptor 2 activity
W. Li
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl023Identification of core 1 O-glycan T-synthase from Caenorhabditis elegans
T. Ju
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl008Isomer and glycomer complexities of core GlcNAcs in Caenorhabditis elegans
A. J. Hanneman
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl011A Mutant Chaperone Converts a Wild-Type Protein into a Tumor-Specific Antigen
A. Schietinger et al.
Original research paper: Science 314
doi:10.1126/science.1129200Characteristics of two CD75-related cell-surface expressed antigens of human lymphocytes
W Eichler
Original research paper: Molecular Immunology 44
doi:10.1016/j.molimm.2006.09.017Use of lectins for probing differentiated human embryonic stem cells for carbohydrates
K. A. Wearne
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl019Neuroglycan C Is a Novel Midkine Receptor Involved in Process Elongation of Oligodendroglial Precursor-like Cells
K. Ichihara-tanaka, A. Oohira, M. Rumsby and T. Muramatsu
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M602228200Siglec-7 Undergoes a Major Conformational Change When Complexed with the (2,8)-Disialylganglioside GT1b
H. Attrill et al.
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M601714200Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene
W. S. Alexander et al.
Original research paper: Proceedings of the National Academy of Sciences 103
doi:10.1073/pnas.0607872103