• January 2007

    • Glycosylation enzyme targeting: A crucial domain

      The length of the transmembrane (TM) domain retains a glycosyltransferase or a glycosidase in a specific region of the Golgi, whereas the composition of cytoplasmic (CT) domain can influence targeting of these enzymes to the endoplasmic reticulum (ER).

      Original research paper: Plant Cell 18, 3182-3200 (2006)
      doi:10.1105/tpc.105.036400

    • T cell fate: Loss of sialic acid in apoptosis

      CD8+ T cell contraction is triggered after an immune response by lectin binding and recognition of sialic acid depleted O-glycans.

      Original research paper: Mol Cell Biol. 27, 1096-1111 (2007)
      doi:10.1128/MCB.01750-06

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