April 2007
Siglecs and their roles in the immune system
Paul R. Crocker, James C. Paulson & Ajit Varki
Original research paper: Nature Reviews Immunology 7 255-266
doi:10.1038/nri2056The crystal structure of two macrolide glycosyltransferases provides a blueprint for host cell antibiotic immunity
D. N. Bolam et al.
Original research paper: Proceedings of the National Academy of Sciences 104
doi:10.1073/pnas.0607897104Tinkering with heparan sulfate sulfation to steer development
B Gorsi & S Stringer
Original research paper: Trends in Cell Biology
doi:10.1016/j.tcb.2007.02.006Langerin is a natural barrier to HIV-1 transmission by Langerhans cells
Lot De witte et al.
Original research paper: Nature Medicine 13 367-371 (2007)
doi:10.1038/nm1541Interaction of the selectin ligand PSGL-1 with chemokines CCL21 and CCL19 facilitates efficient homing of T cells to secondary lymphoid organs
Krystle M Veerman et al.
Original research paper: Nature Immunology
doi:10.1038/ni1456Structures of the Cd44–hyaluronan complex provide insight into a fundamental carbohydrate-protein interaction
Suneale Banerji et al.
Original research paper: Nature Structural & Molecular Biology 14 234-239 (2007)
doi:10.1038/nsmb1201Carbohydrate-binding properties of goat secretory glycoprotein (SPG-40) and its functional implications: structures of the native glycoprotein and its four complexes with chitin-like oligosaccharides
Janesh Kumar et al.
Original research paper: Acta Crystallographica Section D Biological Crystallography 63
doi:10.1107/S0907444907001631HIV entry inhibition by the envelope 2 glycoprotein of GB virus C
Susan Jung et al.
Original research paper: AIDS 21
doi:10.1097/QAD.0b013e32803277c7Analysis of glycans in glycoproteins by diffusion-ordered nuclear magnetic resonance spectroscopy
Karin Ortner, Veeramuthu N. Sivanandam, Wolfgang Buchberger & Norbert Müller
Original research paper: Analytical and Bioanalytical Chemistry 388
doi:10.1007/s00216-007-1232-0Nonlabeled Quartz Crystal Microbalance Biosensor for Bacterial Detection Using Carbohydrate and Lectin Recognitions
Z. Shen et al.
Original research paper: Analytical Chemistry 79
doi:10.1021/ac061986jMutational analysis of the N-glycosylation sites of Duffy antigen/receptor for chemokines
M Czerwinski et al.
Original research paper: Biochemical and Biophysical Research Communications 356
doi:10.1016/j.bbrc.2007.03.054Positive regulation of tumor necrosis factor-α by ganglioside GM3 through Akt in mouse melanoma B16 cells
P Wang et al.
Original research paper: Biochemical and Biophysical Research Communications
doi:10.1016/j.bbrc.2007.02.152Shed gangliosides provide detergent-independent evidence for Type-3 glycosynapses
R Thorne, N Mhaidat, K Ralston & G Burns
Original research paper: Biochemical and Biophysical Research Communications 356
doi:10.1016/j.bbrc.2007.02.139Identification of the nuclear export signals that regulate the intracellular localization of the mouse CMP-sialic acid synthetase
A Fujita, C Sato & K Kitajima
Original research paper: Biochemical and Biophysical Research Communications 355
doi:10.1016/j.bbrc.2007.01.139Drosophila β1,4-N-acetylgalactosaminyltransferase-A synthesizes the LacdiNAc structures on several glycoproteins and glycosphingolipids
N Sasaki et al.
Original research paper: Biochemical and Biophysical Research Communications 354
doi:10.1016/j.bbrc.2007.01.015Identification and expression of a sialyltransferase responsible for the synthesis of disialylgalactosylgloboside in normal and malignant kidney cells: downregulation of ST6GalNAc VI in renal cancers
Motohiro Senda et al.
Original research paper: Biochemical Journal 402
doi:10.1042/BJ20061118Post-translational palmitoylation and glycosylation of Wnt-5a are necessary for its signalling
Manabu Kurayoshi, Hideki Yamamoto, Shunsuke Izumi & Akira Kikuchi
Original research paper: Biochemical Journal 402
doi:10.1042/BJ20061476Kinetic and Structural Studies on Interactions between Heparin or Heparan Sulfate and Proteins of the Hedgehog Signaling Pathway
F. Zhang et al.
Original research paper: Biochemistry 46
doi:10.1021/bi6025424FGFR3 intracellular mutations induce tyrosine phosphorylation in the Golgi and defective glycosylation
L Gibbs & L Legeaimallet
Original research paper: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1773
doi:10.1016/j.bbamcr.2006.12.010Structural characterization of a rhamnose-binding glycoprotein (lectin) from Spanish mackerel (Scomberomorous niphonius) eggs
T Terada et al.
Original research paper: Biochimica et Biophysica Acta (BBA) - General Subjects 1770
doi:10.1016/j.bbagen.2006.11.003Comparative rates of sialylation by recombinant trans-sialidase and inhibitor properties of synthetic oligosaccharides from Trypanosoma cruzi mucins-containing galactofuranose and galactopyranose
R Agusti et al.
Original research paper: Bioorganic & Medicinal Chemistry 15
doi:10.1016/j.bmc.2007.01.045Variations in glycosylation of von Willebrand factor with O-linked sialylated T antigen are associated with its plasma levels
C. J. M. Van schooten et al.
Original research paper: Blood 109
doi:10.1182/blood-2006-06-032706Synthesis of glycosylated human tumor necrosis factor α coupled with N-acetylneuraminic acid
Akiko Hayashi et al.
Original research paper: Cancer Immunology, Immunotherapy 56
doi:10.1007/s00262-006-0209-8Regulation of galectin-1 expression by transforming growth factor β1 in metastatic mammary adenocarcinoma cells: implications for tumor-immune escape
Cecilia M. Daroqui et al.
Original research paper: Cancer Immunology, Immunotherapy 56
doi:10.1007/s00262-006-0208-9Glycoconjugate profiling of primary melanoma and its sentinel node and distant metastases: Implications for diagnosis and pathophysiology of metastases
A Thies et al.
Original research paper: Cancer Letters 248
doi:10.1016/j.canlet.2006.05.020LC-MS/MS Quantification of Zn-α2 Glycoprotein: A Potential Serum Biomarker for Prostate Cancer
O. P. Bondar et al.
Original research paper: Clinical Chemistry 53
doi:10.1373/clinchem.2006.079681Sialic acids: carbohydrate moieties that influence the biological and physical properties of biopharmaceutical proteins and living cells
B Byrne, G Donohoe & R Okennedy
Original research paper: Drug Discovery Today 12
doi:10.1016/j.drudis.2007.02.010Glypican-3: From the mutations of Simpson–Golabi–Behmel genetic syndrome to a tumor marker for hepatocellular carcinoma
B Jakubovic & S Jothy
Original research paper: Experimental and Molecular Pathology 82
doi:10.1016/j.yexmp.2006.10.010Matrix metalloproteinases and proteoglycans in axonal regeneration
M Pizzi & M Crowe
Original research paper: Experimental Neurology 204
doi:10.1016/j.expneurol.2006.12.012PANVACTM-VF: poxviral-based vaccine therapy targeting CEA and MUC1 in carcinoma
Ravi A Madan, Philip M Arlen & James L Gulley
Original research paper: Expert Opinion on Biological Therapy 7
doi:10.1517/14712598.7.4.543Ammonia secretion from fish gill depends on a set of Rh glycoproteins
T. Nakada, C. M. Westhoff, A. Kato & S. Hirose
Original research paper: The FASEB Journal 21
doi:10.1096/fj.06-6834comMannan-modified adenovirus as a vaccine to induce antitumor immunity
Z-Y Ding et al.
Original research paper: Gene Therapy 14 657-663 (2007)
doi:10.1038/sj.gt.3302893Glycosylation and palmitoylation of Wnt-3a are coupled to produce an active form of Wnt-3a
Hideyuki Komekado, Hideki Yamamoto, Tsutomu Chiba & Akira Kikuchi
Original research paper: Genes to Cells 12
doi:10.1111/j.1365-2443.2007.01068.xPurification and structural characterization of de-N-acetylated form of GD3 ganglioside present in human melanoma tumors
I. Popa et al.
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwm006Glycosylation of serum ribonuclease 1 indicates a major endothelial origin and reveals an increase in core fucosylation in pancreatic cancer
S. Barrabes et al.
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwm002Comparison of the methods for profiling glycoprotein glycans--HUPO Human Disease Glycomics/Proteome Initiative multi-institutional study
Y. Wada et al.
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwl086Carbohydrate-recognition domains of galectin-9 are involved in intermolecular interaction with galectin-9 itself and other members of the galectin family
N. Miyanishi et al.
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwm001The lectin domains of polypeptide GalNAc-transferases exhibit carbohydrate-binding specificity for GalNAc: lectin binding to GalNAc-glycopeptide substrates is required for high density GalNAc-O-glycosylation
H. H. Wandall et al.
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwl082Virus-induced transcriptional activation of host FUT genes associated with neo-expression of Ley in cytomegalovirus-infected and sialyl-Lex in varicella-zoster virus-infected diploid human cells
K. Nystrom et al.
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwl083Reduced sialylation status in UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase (GNE)-deficient mice
Daniel Gagiannis et al.
Original research paper: Glycoconjugate Journal 24
doi:10.1007/s10719-006-9019-7Expression of β-1,4-Galactosyltransferase-I in Rat during Inflammation
Ji Qian et al.
Original research paper: Inflammation 30
doi:10.1007/s10753-007-9022-6Modifications of surface carbohydrates on bovine spermatozoa mediated by oviductal fluid: a flow cytometric study using lectins
Ioannis A. Taitzoglou, Alexandra N. Kokoli & Gary J. Killian
Original research paper: International Journal of Andrology 30
doi:10.1111/j.1365-2605.2006.00717.xChondroitin sulfate glycosaminoglycans as major P-selectin ligands on metastatic breast cancer cell lines
Behjatolah Monzavi-karbassi et al.
Original research paper: International Journal of Cancer 120
doi:10.1002/ijc.22424Site-Specific Incorporation of Glycosylated Serine and Tyrosine Derivatives into Proteins
N.E. Fahmi et al.
Original research paper: Journal of the American Chemical Society 129
doi:10.1021/ja067466nAutomated Synthesis of the Tumor-Associated Carbohydrate Antigens Gb-3 and Globo-H: Incorporation of α-Galactosidic Linkages
D.B. Werz, B. Castagner & P.H. Seeberger
Original research paper: Journal of the American Chemical Society 129
doi:10.1021/ja069218xGolgi GDP-fucose Transporter-deficient Mice Mimic Congenital Disorder of Glycosylation IIc/Leukocyte Adhesion Deficiency II
C. C. Hellbusch et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M700314200Identification of a Glycosaminoglycan Binding Region of the Alpha C Protein That Mediates Entry of Group B Streptococci into Host Cells
M. J. Baron et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M608279200Impact of Carrier Stiffness and Microtopology on Two-dimensional Kinetics of P-selectin and P-selectin Glycoprotein Ligand-1 (PSGL-1) Interactions
L. Wu et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M609219200Structural Effects of Naturally Occurring Human Blood Group B Galactosyltransferase Mutations Adjacent to the DXD Motif
M. Persson et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M610998200Structure and Mechanism of Helicobacter pylori Fucosyltransferase: A BASIS FOR LIPOPOLYSACCHARIDE VARIATION AND INHIBITOR DESIGN
H.-Y. Sun et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M610285200Dynamic Developmental Elaboration of N-Linked Glycan Complexity in the Drosophila melanogaster Embryo
K. Aoki et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M606711200Expression of rib-1, a Caenorhabditis elegans Homolog of the Human Tumor Suppressor EXT Genes, Is Indispensable for Heparan Sulfate Synthesis and Embryonic Morphogenesis
H. Kitagawa et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M611107200Ganglioside GM2-Tetraspanin CD82 Complex Inhibits Met and Its Cross-talk with Integrins, Providing a Basis for Control of Cell Motility through Glycosynapse
A. R. Todeschini, J. N. Dos santos, K. Handa & S.-i. Hakomori
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M611407200Ganglioside GD1a Is an Essential Coreceptor for Toll-like Receptor 2 Signaling in Response to the B subunit of Type IIb Enterotoxin
S. Liang et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M611722200Human Follicular Lymphoma Cells Contain Oligomannose Glycans in the Antigen-binding Site of the B-cell Receptor
C. M. Radcliffe et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M602690200Serine scanning—A tool to prove the consequences of N-glycosylation of proteins
R Weis, R Gaisberger, K Gruber & A Glieder
Original research paper: Journal of Biotechnology 129
doi:10.1016/j.jbiotec.2006.12.001Alternative isoforms of myelin/oligodendrocyte glycoprotein with variable cytoplasmic domains are expressed in human brain
Chantal Allamargot & Minnetta V. Gardinier
Original research paper: Journal of Neurochemistry 101
doi:10.1111/j.1471-4159.2006.04296.xConformational Behavior of Basic Monomeric Building Units of Glycosaminoglycans: Isolated Systems and Solvent Effect
M. Remko, M. Swart & F.M. Bickelhaupt
Original research paper: Journal of Physical Chemistry B 111
doi:10.1021/jp0646271Mutation in the Glycosylated Gag Protein of Murine Leukemia Virus Results in Reduced In Vivo Infectivity and a Novel Defect in Viral Budding or Release
A. Low et al.
Original research paper: Journal of Virology 81
doi:10.1128/JVI.01538-06Antigenic and Mutational Analyses of Herpes Simplex Virus Glycoprotein B Reveal Four Functional Regions
F. C. Bender et al.
Original research paper: Journal of Virology 81
doi:10.1128/JVI.02710-06A Second Receptor Binding Site on Human Parainfluenza Virus Type 3 Hemagglutinin-Neuraminidase Contributes to Activation of the Fusion Mechanism
M. Porotto, M. Fornabaio, G. E. Kellogg & A. Moscona
Original research paper: Journal of Virology 81
doi:10.1128/JVI.02617-06Sialic Acid on Herpes Simplex Virus Type 1 Envelope Glycoproteins Is Required for Efficient Infection of Cells
J. R. Teuton & C. R. Brandt
Original research paper: Journal of Virology 81
doi:10.1128/JVI.02250-06Heparan and chondroitin sulfate on growth plate perlecan mediate binding and delivery of FGF-2 to FGF receptors
S Smith et al.
Original research paper: Matrix Biology 26
doi:10.1016/j.matbio.2006.10.012Scanning N-glycosylation mutagenesis of membrane proteins
J Cheung & R Reithmeier
Original research paper: Methods 41
doi:10.1016/j.ymeth.2006.10.002Gangliosides, Ab1 and Ab2 antibodiesIV. Dominance of VH domain in the induction of anti-idiotypic antibodies by gene gun immunization
A Lopezrequena et al.
Original research paper: Molecular Immunology 44
doi:10.1016/j.molimm.2007.01.020Drosophila C-type lectins enhance cellular encapsulation
J Ao, E Ling & X Yu
Original research paper: Molecular Immunology 44
doi:10.1016/j.molimm.2006.12.024Reactivities of N-acetylgalactosamine-specific lectins with human IgA1 proteins
J Moore et al.
Original research paper: Molecular Immunology 44
doi:10.1016/j.molimm.2006.12.011Rolling on N-linked glycans: a new way to present L-selectin binding sites
Ronen Alon & Steven Rosen
Original research paper: Nature Immunology 8 339-341
doi:10.1038/ni0407-339Critical functions of N-glycans in L-selectin-mediated lymphocyte homing and recruitment
Junya Mitoma et al.
Original research paper: Nature Immunology 8 409-418 (2007)
doi:10.1038/ni1442Glycan chains modulate prion protein binding to immobilized metal ions
M Moudjou et al.
Original research paper: Neurochemistry International 50
doi:10.1016/j.neuint.2007.01.001The conformational behaviour and P-selectin inhibition of fluorine-containing sialyl LeX glycomimetics
Javier Pérez-castells et al.
Original research paper: Organic & Biomolecular Chemistry 5
doi:10.1039/b615752aCarbohydrate post-glycosylational modifications
Hai Yu & Xi Chen
Original research paper: Organic & Biomolecular Chemistry 5
doi:10.1039/b700034kNeoglycopeptide Dendrimer Libraries as a Source of Lectin Binding Ligands
E. Kolomiets et al.
Original research paper: Organic Letters 9
doi:10.1021/ol070119dGlycosaminoglycan Interactions in Murine Gammaherpesvirus-68 Infection
Laurent Gillet, Heiko Adler, Philip G. Stevenson & Olivier Schwartz
Original research paper: PLoS ONE 2
doi:10.1371/journal.pone.0000347Structural basis for the selection of glycosylated substrates by SCFFbs1 ubiquitin ligase
T. Mizushima et al.
Original research paper: Proceedings of the National Academy of Sciences 104
doi:10.1073/pnas.0610312104Crystal structure of a peptidoglycan glycosyltransferase suggests a model for processive glycan chain synthesis
Y. Yuan et al.
Original research paper: Proceedings of the National Academy of Sciences 104
doi:10.1073/pnas.0701160104Noninfectious entry of HIV-1 into peripheral and brain macrophages mediated by the mannose receptor
J. R. Trujillo et al.
Original research paper: Proceedings of the National Academy of Sciences 104
doi:10.1073/pnas.0611263104Separation of receptor-binding and profusogenic domains of glycoprotein D of herpes simplex virus 1 into distinct interacting proteins
G. Zhou & B. Roizman
Original research paper: Proceedings of the National Academy of Sciences 104
doi:10.1073/pnas.0611565104Apical Sorting by Galectin-3-Dependent Glycoprotein Clustering
Delphine Delacour et al.
Original research paper: Traffic 8
doi:10.1111/j.1600-0854.2007.00539.xIntegrating transcriptome, proteome and glycome analyses of Schistosoma biology
C Hokke, J Fitzpatrick & K Hoffmann
Original research paper: Trends in Parasitology 23
doi:10.1016/j.pt.2007.02.007Carbohydrate profiling and protein identification of tegumental and excreted/secreted glycoproteins of adult Schistosoma bovis worms
A Ramajohernandez, A Oleaga, V Ramajomartin & R Perezsanchez
Original research paper: Veterinary Parasitology 144
doi:10.1016/j.vetpar.2006.09.034Antigenicity and immunogenicity of HIV-1 consensus subtype B envelope glycoproteins
D Kothe et al.
Original research paper: Virology 360
doi:10.1016/j.virol.2006.10.017Specific amino acids in the N-terminus of the gp41 ectodomain contribute to the stabilization of a soluble, cleaved gp140 envelope glycoprotein from human immunodeficiency virus type 1
A Dey, K David, P Klasse & J Moore
Original research paper: Virology 360
doi:10.1016/j.virol.2006.09.046Characterization of the Epstein–Barr virus glycoprotein BMRF-2
J Xiao, J Palefsky, R Herrera & S Tugizov
Original research paper: Virology 359
doi:10.1016/j.virol.2006.09.047Synthesis of complex-type glycans derived from parasitic helminths
J Nakano, A Ishiwata, H Ohta & Y Ito
Original research paper: Carbohydrate Research 342
doi:10.1016/j.carres.2006.12.022Functionalization of oligosaccharide mimetics and multimerization using squaric diester-mediated coupling
O Sperling, M Dubber & T Lindhorst
Original research paper: Carbohydrate Research 342
doi:10.1016/j.carres.2006.12.021Structure elucidation of arabinoxylan isomers by normal phase HPLC–MALDI-TOF/TOF-MS/MS
S Maslen et al.
Original research paper: Carbohydrate Research 342
doi:10.1016/j.carres.2006.12.007Unexpected regioselectivity of Humicola insolens Cel7B glycosynthase mutants
S Blanchard et al.
Original research paper: Carbohydrate Research 342
doi:10.1016/j.carres.2006.12.017The O-chain structure from the LPS of the bacterium Naxibacter alkalitolerans YIM 31775T
A Silipo et al.
Original research paper: Carbohydrate Research 342
doi:10.1016/j.carres.2006.12.012