June 2007

• Glycosylation effects: Core contributions

  Distant carbohydrate substitutions at the N-glycan core alter glycan lectin affinity, glycoprotein-mediated cell binding and serum clearance.

  Original research paper: Biochemistry 46, 6984-6995 (2007)
  doi:10.1021/bi7000467

• Tumor growth: At the end of a snake bite

  The C-type lectins lebectin and lebecetin isolated from the venom of the blunt-nosed viper (Macrovipera lebetina) have been shown to inhibit tumor angiogenesis through a direct interaction with epithelial cell integrins.

  Original research paper: J Cell Physiol. 211, 307-315 (2007)
  doi:10.1021/jcp.20935