March 2008
Drug development: Sweet talk to receptors
Using glycan ligand engineering to target carbohydrate-binding receptors is a promising strategy for stem cell therapy and cancer immunotherapy.
Original research paper: Nature Medicine 14, 181-187 (2008)
doi:10.1038/nm1703Dendritic cell receptors: Keeping it in the family
The dendritic cell (DC) C-lectin-like immune receptor (DCIR) is closely related to other C-lectin like receptors (CLRs) in its antigen presentation function and inhibitory cross talk with Toll-like receptors (TLRs).
Original research paper: Nature Medicine 14, 176-180 (2008)
doi:10.1038/nm1697