• April 2008

    • Quality control: Lectins ERADicate misfolded proteins

      OS-9 and XTP3-B are lectins residing in the lumen of the endoplasmatic reticulum (ER) that deliver misfolded proteins to the ubiquitin ligase complex SEL1/Hrd1.

      Functional Glycomics Gateway (2008)
      doi:10.1038/fg.2008.19

    • Migration and anergy: The lattice strikes again

      Cell surface galectin-glycan lattices (GGL), formed from galectin-3 (Gal-3) and beta-galactoside ligands, regulate focal adhesion (FA) formation and disrupt the association of T-cell receptor (TCR) with CD8 in cytolytic lymphocytes (CTLs).

      Functional Glycomics Gateway (2008)
      doi:10.1038/fg.2008.20

    • Glycan-lectin binding: The polyvalent value of viruses

      Glycan ligands can be built onto virus particles in a polyvalent fashion, which enables their binding to lectin receptors.

      Functional Glycomics Gateway (2008)
      doi:10.1038/fg.2008.21

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