September 2008

• Proteoglycan editing: Sulfatases change a frog's fate

  Extracellular sulfatases edit cell-surface heparan sulfate proteoglycans, thereby modulating signaling pathways that determine Xenopus tropicalis development.

  Original research paper: Developmental Biology 320, 436-445 (2008)
  

• Golgi protein glycosylation: Keeping transferases safe and sound

  The COSMC chaperone enables the formation of functional T-synthase dimers active in the Golgi apparatus, and most yeast Golgi glycosyltransferases are localized to their compartment by binding to the coat protein I linker Vps74p.

  Original research paper: Journal of Cell Biology 182, 531-542 (2008)
  doi:10.1083/jcb.200711151