May 2009

• GlcNAcylation: RAREing to go

  Glycosylation is now implicated in the epigenetic control of transcription, increasing the cellular response to retinoic acid by activation of a histone-modifying nuclear protein.

  Original research paper: Nature (published online 19 Apr 2009)
  doi:10.1038/nature07954

• Chondroitin sulfate: Driving bone development

  Sulfated chondroitin sulfate and heparan sulfate proteoglycans cooperatively influence a signaling pathway necessary for proper bone growth.

  Original research paper: Development 136, 1697-1706 (2009)
  doi:10.1242/dev.030742