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Original publication name: GM2/GD2 Synthase

Colony code name: GM

Gene symbols: Galgt1

Gene name(s): Gal-NAc-T, GalNAc-T, GalNAcT, Ggm-2, Ggm2, GM2/GD2 synthase

Protein name: P-N-acetyl-a-D-galactosamine:(N-acetylneuraminyl)-galactosylglucosylceramide-b-1,4-N-acetylgalactosaminyltransferase

Chromosome: 10

Reported function: (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase

Genomic DNA source: 129/Sv

Mutation type: Neo replacement of exon 6,7 and part of 8

ES cell line: TC1 (Deng C, et al. Cell. 1996;84:911-921. [PubMed])

Current genetic background: 94% C57Bl/6 (as determined by whole genome scan)

Breeding phenotype: Homozygous males are sterile

Name of contributing investigator: R. Proia

Name of institution: National Institutes of Health, Genetics of Development and Disease Branch

Primary reference: Liu Y, et al. J Clin Inv. 1999;103:497-505. [PubMed]





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